papular xanthoma
Findings
No curated finding names papular xanthoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Papular xanthoma is a form of non-Langerhans cell histiocytosis characterized by cutaneous presentation of solitary or disseminated yellow to orange-brown papular or papulonodular, noncoalescent, asymptomatic skin lesions located predominantly on the head, neck, trunk and extremities (rarely on oral mucosa), in the presence of normolipidemia. Microscopically, the lesions consist of monomorphous infiltrate of xanthomatized macrophages and numerous Touton giant cells, with scant or absent inflammatory infiltrate. It is usually not associated with systemic disease.
Definition from the Mondo Disease Ontology (MONDO:0015536), read 2026-09-29. CC BY 4.0.
Features
3 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Eruptive xanthomasHPOHP:0001013
- Very frequent (80% to 99% of cases)
- HistiocytosisHPOHP:0100727
- Very frequent (80% to 99% of cases)
- Skin plaqueHPOHP:0200035
- Very frequent (80% to 99% of cases)
Reported absent (1)
- HyperlipidemiaHPOHP:0003077
Where it sits
- A kind of