overlap myositis
MONDO:0016099Mondo
Findings
No curated finding names overlap myositis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Overlap myositis (OM) is a form of idiopathic inflammatory myopathy (IIM) characterized by myositis with at least one clinical and/or autoantibody overlap feature.
Definition from the Mondo Disease Ontology (MONDO:0016099), read 2026-09-29. CC BY 4.0.
Features
40 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal circulating lipid concentrationHPOHP:0003119
- Frequent (30% to 79% of cases)
- Anti-Ku antibody positivityHPOHP:0034088
- Frequent (30% to 79% of cases)
- Anti-PM-Scl antibody positivityHPOHP:0033560
- Frequent (30% to 79% of cases)
- Anti-Ro/SS-A antibody positivityHPOHP:0033555
- Frequent (30% to 79% of cases)
- Anti-Ro52/TRIM21 antibody positivityHPOHP:0034093
- Frequent (30% to 79% of cases)
- Anti-Sm antibody positivityHPOHP:0033040
- Frequent (30% to 79% of cases)
- Anti-topoisomerase I antibody positivityHPOHP:0030859
- Frequent (30% to 79% of cases)
- Antinuclear antibody positivityHPOHP:0003493
- Frequent (30% to 79% of cases)
- ArthritisHPOHP:0001369
- Frequent (30% to 79% of cases)
- AutoimmunityHPOHP:0002960
- Frequent (30% to 79% of cases)
- Constitutional symptomHPOHP:0025142
- Frequent (30% to 79% of cases)
- DysphagiaHPOHP:0002015
- Frequent (30% to 79% of cases)
Show the remaining 28
- Elevated circulating creatine kinase activityHPOHP:0003236
- Frequent (30% to 79% of cases)
- Finger swellingHPOHP:0025131
- Frequent (30% to 79% of cases)
- HypertensionHPOHP:0000822
- Frequent (30% to 79% of cases)
- Perifascicular muscle fiber atrophyHPOHP:0100296
- Frequent (30% to 79% of cases)
- Proximal muscle weaknessHPOHP:0003701
- Frequent (30% to 79% of cases)
- Proximal upper limb muscle weaknessHPOHP:0008997
- Frequent (30% to 79% of cases)
Where it sits
Other names
2 names
Resolves to: overlap myositis
- Also called
- adult-onset overlap myositisnon-specific myositis