ovarian gonadoblastoma
Findings
No curated finding names ovarian gonadoblastoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A neoplasm that arises from the ovary and is composed of tissues that resemble dysgerminoma or seminoma and are admixed with sex cord tissues. It is found in children or young adults and usually is associated with secondary sex organs abnormalities. The majority of patients present as phenotypic females with virilization. The minority of patients present as phenotypic males with feminization. It typically affects both gonads. If a malignant germ cell component is present, it may metastasize to other anatomic sites.
Definition from the Mondo Disease Ontology (MONDO:0002697), read 2026-09-29. CC BY 4.0.
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormality of the ovaryHPOHP:0000137
- Very frequent (80% to 99% of cases)
- Female external genitalia in individual with 46,XY karyotypeHPOHP:0008730
- Very frequent (80% to 99% of cases)
- Ovarian gonadoblastomaHPOHP:0000149
- Very frequent (80% to 99% of cases)
- DysgerminomaHPOHP:0100621
- Frequent (30% to 79% of cases)
- Gonadal calcificationHPOHP:0008703
- Frequent (30% to 79% of cases)
- Gonadal dysgenesis with female appearance, maleHPOHP:0008723
- Frequent (30% to 79% of cases)
Where it sits
Other names
3 names
Resolves to: ovarian gonadoblastoma
- Also called
- gonadoblastoma of ovaryovarian gonadoblastoma (disease)ovary gonadoblastoma