ovarian cancer
MONDO:0008170Mondo
Findings
No curated finding names ovarian cancer yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A primary or metastatic malignant neoplasm involving the ovary. Most primary malignant ovarian neoplasms are either carcinomas (serous, mucinous, or endometrioid adenocarcinomas) or malignant germ cell tumors. Metastatic malignant neoplasms to the ovary include carcinomas, lymphomas, and melanomas.
Definition from the Mondo Disease Ontology (MONDO:0008170), read 2026-09-29. CC BY 4.0.
Genes
6 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- MLH1HGNC:7127
- Strong · Genomics England PanelApp · Autosomal dominant · 2020
- MSH2HGNC:7325
- Strong · Genomics England PanelApp · Autosomal dominant · 2020
- MSH6HGNC:7329
- Strong · Genomics England PanelApp · Autosomal dominant · 2020
- PMS2HGNC:9122
- Moderate · Genomics England PanelApp · Autosomal dominant · 2020
- FANCCHGNC:3584
- Limited · Ambry Genetics · Autosomal dominant · 2022
- RRAS2HGNC:17271
- No Known Disease Relationship · Ambry Genetics · Unknown · 2019
Where it sits
- Narrower terms (11)
Other names
16 names
Resolves to: ovarian cancer
- Also called
- cancer of ovarycancer of the ovarymalignant neoplasm of ovarymalignant neoplasm of the ovarymalignant ovarian neoplasmmalignant ovarian tumormalignant ovarian tumourmalignant ovary neoplasmmalignant tumor of ovarymalignant tumor of the ovarymalignant tumour of ovarymalignant tumour of the ovaryovarian cancer, somaticovarian malignant tumorovarian malignant tumourovary cancer