optic pathway glioma
Findings
No curated finding names optic pathway glioma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Optic pathway glioma (OPG) is a benign tumor that develop along the optic nerve (chiasm, tracts, and radiations) characterized by impairment or loss of vision and may be accompanied by diencephalic symptoms such as reduced growth and alteration in sleeping patterns. OPG are often linked to neurofibromatosis type 1 (NF1).
Definition from the Mondo Disease Ontology (MONDO:0016167), read 2026-09-29. CC BY 4.0.
Features
23 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- NeurofibromaHPOHP:0001067
- Frequent (30% to 79% of cases)
- NystagmusHPOHP:0000639
- Frequent (30% to 79% of cases)
- Optic atrophyHPOHP:0000648
- Frequent (30% to 79% of cases)
- Reduced visual acuityHPOHP:0007663
- Frequent (30% to 79% of cases)
- Visual lossHPOHP:0000572
- Frequent (30% to 79% of cases)
- Abnormality of the nervous systemHPOHP:0000707
- Occasional (5% to 29% of cases)
- BlindnessHPOHP:0000618
- Occasional (5% to 29% of cases)
- Developmental regressionHPOHP:0002376
- Occasional (5% to 29% of cases)
- Fatigable weaknessHPOHP:0003473
- Occasional (5% to 29% of cases)
- Global developmental delayHPOHP:0001263
- Occasional (5% to 29% of cases)
- Growth delayHPOHP:0001510
- Occasional (5% to 29% of cases)
- HeadacheHPOHP:0002315
- Occasional (5% to 29% of cases)
Show the remaining 11
- HydrocephalusHPOHP:0000238
- Occasional (5% to 29% of cases)
- NauseaHPOHP:0002018
- Occasional (5% to 29% of cases)
- OphthalmoplegiaHPOHP:0000602
- Occasional (5% to 29% of cases)
- PapilledemaHPOHP:0001085
- Occasional (5% to 29% of cases)
- Precocious pubertyHPOHP:0000826
- Occasional (5% to 29% of cases)
- ProptosisHPOHP:0000520
- Occasional (5% to 29% of cases)
Where it sits
- Narrower terms (2)
Other names
6 names
Resolves to: optic pathway glioma
- Also called
- glioma of optic tractglioma of the optic tractglioma of the visual pathwayglioma of visual pathwayoptic tract gliomavisual pathway glioma