opsoclonus-myoclonus syndrome
MONDO:0015247Mondo
Findings
No curated finding names opsoclonus-myoclonus syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Opsoclonus myoclonus syndrome (OMS) is a rare neuroinflammatory disease of paraneoplastic, parainfectious or idiopathic origin, characterized by opsoclonus, myoclonus, ataxia, and behavioral and sleep disorders.
Definition from the Mondo Disease Ontology (MONDO:0015247), read 2026-09-29. CC BY 4.0.
Features
22 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal saccadic eye movementsHPOHP:0000570
- Very frequent (80% to 99% of cases)
- AtaxiaHPOHP:0001251
- Very frequent (80% to 99% of cases)
- MyoclonusHPOHP:0001336
- Very frequent (80% to 99% of cases)
- OpsoclonusHPOHP:0010543
- Very frequent (80% to 99% of cases)
- Sleep disturbanceHPOHP:0002360
- Very frequent (80% to 99% of cases)
- Anti-Amphiphysin antibodyHPOHP:5000002
- Frequent (30% to 79% of cases)
- Atypical behaviorHPOHP:0000708
- Frequent (30% to 79% of cases)
- Cognitive impairmentHPOHP:0100543
- Frequent (30% to 79% of cases)
- IrritabilityHPOHP:0000737
- Frequent (30% to 79% of cases)
- Limb myoclonusHPOHP:0045084
- Frequent (30% to 79% of cases)
- NeoplasmHPOHP:0002664
- Frequent (30% to 79% of cases)
- NeuroblastomaHPOHP:0003006
- Frequent (30% to 79% of cases)
Show the remaining 10
- VertigoHPOHP:0002321
- Frequent (30% to 79% of cases)
- Autoimmune antibody positivityHPOHP:0030057
- Occasional (5% to 29% of cases)
- Breast carcinomaHPOHP:0003002
- Occasional (5% to 29% of cases)
- Chronic infectionHPOHP:0031035
- Occasional (5% to 29% of cases)
- EncephalopathyHPOHP:0001298
- Occasional (5% to 29% of cases)
- MelanomaHPOHP:0002861
- Occasional (5% to 29% of cases)
Where it sits
Other names
11 names
Resolves to: opsoclonus-myoclonus syndrome
- Also called
- Ataxo-opso-myoclonus syndromedancing eye syndromedancing eye-dancing feet syndromeKinsbourne syndromeoma syndromeOMSopsoclonus myoclonus syndromeOpsoclonus-Myoclonus-Ataxia Syndromeparaneoplastic opsoclonus-myoclonusparaneoplastic opsoclonus-myoclonus-ataxia syndromePOMA syndrome