oligomeganephronia
MONDO:0016407Mondo
Findings
No curated finding names oligomeganephronia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Oligomeganephronia is a developmental anomaly of the kidneys, and the most severe form of renal hypoplasia, characterized by a reduction of 80% in nephron number and a marked hypertrophy of the glomeruli and tubules.
Definition from the Mondo Disease Ontology (MONDO:0016407), read 2026-09-29. CC BY 4.0.
Features
30 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal nephron morphologyHPOHP:0012575
- Very frequent (80% to 99% of cases)
- Bilateral renal hypoplasiaHPOHP:0012584
- Very frequent (80% to 99% of cases)
- Decreased glomerular filtration rateHPOHP:0012213
- Very frequent (80% to 99% of cases)
- Decreased numbers of nephronsHPOHP:0005563
- Very frequent (80% to 99% of cases)
- Elevated circulating creatinine concentrationHPOHP:0003259
- Very frequent (80% to 99% of cases)
- GlomerulomegalyHPOHP:0030162
- Very frequent (80% to 99% of cases)
- ProteinuriaHPOHP:0000093
- Very frequent (80% to 99% of cases)
- Renal insufficiencyHPOHP:0000083
- Very frequent (80% to 99% of cases)
- Abnormal medullary pyramid morphologyHPOHP:0025361
- Frequent (30% to 79% of cases)
- Abnormal renal cortex morphologyHPOHP:0011035
- Frequent (30% to 79% of cases)
- Premature birthHPOHP:0001622
- Frequent (30% to 79% of cases)
- Renal tubular atrophyHPOHP:0000092
- Frequent (30% to 79% of cases)
Show the remaining 18
- Small for gestational ageHPOHP:0001518
- Frequent (30% to 79% of cases)
- Stage 5 chronic kidney diseaseHPOHP:0003774
- Frequent (30% to 79% of cases)
- DehydrationHPOHP:0001944
- Occasional (5% to 29% of cases)
- PolydipsiaHPOHP:0001959
- Occasional (5% to 29% of cases)
- Abnormality of limbsHPOHP:0040064
- Very rare (1% to 4% of cases)
- Abnormality of the faceHPOHP:0000271
- Very rare (1% to 4% of cases)
Where it sits
- A kind of
Other names
1 name
Resolves to: oligomeganephronia
- Also called
- Oligomeganephronic renal hypoplasia