Noonan syndrome with multiple lentigines

Findings

No curated finding names Noonan syndrome with multiple lentigines yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.

Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.

Where it sits

A kind of

• autosomal dominant disease
• multiple congenital anomalies/dysmorphic syndrome without intellectual disability
• Noonan syndrome and Noonan-related syndrome
• syndromic disease

Narrower terms (3)

• LEOPARD syndrome 1
• LEOPARD syndrome 2
• LEOPARD syndrome 3

Resolves to: Noonan syndrome with multiple lentigines

Also called

Cardiomyopathic lentiginosisfamilial multiple lentigines syndromegeneralised lentiginosislentigines, electrocardiographic conduction defects, 0cular hypertelorism, pulmonary stenosis, abnormalities of the genitals, retarded Growth, deafnessLEOPARD syndrome