nodular non-suppurative panniculitis
MONDO:0018063Mondo
Findings
No curated finding names nodular non-suppurative panniculitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Nodular non-suppurative panniculitis, known as Weber-Christian disease (WCD), is a rare skin disorder characterized by recurring inflammation in the subcutaneous layer of fat.
Definition from the Mondo Disease Ontology (MONDO:0018063), read 2026-09-29. CC BY 4.0.
Features
15 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abdominal painHPOHP:0002027
- Very frequent (80% to 99% of cases)
- Aplasia/Hypoplasia of the skinHPOHP:0008065
- Very frequent (80% to 99% of cases)
- ArthralgiaHPOHP:0002829
- Very frequent (80% to 99% of cases)
- EdemaHPOHP:0000969
- Very frequent (80% to 99% of cases)
- ErythemaHPOHP:0010783
- Very frequent (80% to 99% of cases)
- FeverHPOHP:0001945
- Very frequent (80% to 99% of cases)
- MyalgiaHPOHP:0003326
- Very frequent (80% to 99% of cases)
- Nausea and vomitingHPOHP:0002017
- Very frequent (80% to 99% of cases)
- PanniculitisHPOHP:0012490
- Very frequent (80% to 99% of cases)
- Subcutaneous noduleHPOHP:0001482
- Very frequent (80% to 99% of cases)
- Weight lossHPOHP:0001824
- Very frequent (80% to 99% of cases)
- AutoimmunityHPOHP:0002960
- Occasional (5% to 29% of cases)
Show the remaining 3
- HepatomegalyHPOHP:0002240
- Occasional (5% to 29% of cases)
- Inflammatory abnormality of the eyeHPOHP:0100533
- Occasional (5% to 29% of cases)
- SplenomegalyHPOHP:0001744
- Occasional (5% to 29% of cases)
Where it sits
Other names
9 names
Resolves to: nodular non-suppurative panniculitis
- Also called
- idiopathic lobular panniculitisidiopathic nodular panniculitisnodular nonsuppurative panniculitisPfeiffer-Weber-Christian syndromeRelapsing febrile nodular nonsuppurative panniculitisRelapsing febrile nodular panniculitisWCDWeber-Christian diseaseWeber-Christian panniculitis