NK-cell enteropathy
MONDO:0016996Mondo
Findings
No curated finding names NK-cell enteropathy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Natural killer (NK)-cell enteropathy is a benign NK-cell lymphoproliferative disease characterized by minor abdominal symptoms (abdominal pain, diverticulosis, constipation and reflux) due to NK cell-derived lesions in the mucosal layer of the gastrointestinal tract and often mistaken for NK or T-cell lymphoma.
Definition from the Mondo Disease Ontology (MONDO:0016996), read 2026-09-29. CC BY 4.0.
Features
14 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- EdemaHPOHP:0000969
- Very frequent (80% to 99% of cases)
- Increased total T cell countHPOHP:0100828
- Very frequent (80% to 99% of cases)
- Lymphoproliferative disorderHPOHP:0005523
- Very frequent (80% to 99% of cases)
- Abdominal painHPOHP:0002027
- Frequent (30% to 79% of cases)
- Abnormal gastric mucosa morphologyHPOHP:0004295
- Occasional (5% to 29% of cases)
- Colonic diverticulaHPOHP:0002253
- Occasional (5% to 29% of cases)
- ConstipationHPOHP:0002019
- Occasional (5% to 29% of cases)
- DiarrheaHPOHP:0002014
- Occasional (5% to 29% of cases)
- Duodenal ulcerHPOHP:0002588
- Occasional (5% to 29% of cases)
- Gastric ulcerHPOHP:0002592
- Occasional (5% to 29% of cases)
- Gastroesophageal refluxHPOHP:0002020
- Occasional (5% to 29% of cases)
- HematocheziaHPOHP:0002573
- Occasional (5% to 29% of cases)
Show the remaining 2
- Intestinal polypHPOHP:0005266
- Occasional (5% to 29% of cases)
- Stercoral ulcerHPOHP:0012425
- Occasional (5% to 29% of cases)
Where it sits
- A kind of