neurotrophic keratopathy
MONDO:0015290Mondo
Findings
No curated finding names neurotrophic keratopathy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Neurotrophic keratopathy is a rare degenerative disease of the cornea characterized by reduction or loss of corneal sensitivity that can be asymptomatic or present with red-eye and, during the early stages of the disease, a minor decrease in visual acuity. It eventually leads to loss of vision.
Definition from the Mondo Disease Ontology (MONDO:0015290), read 2026-09-29. CC BY 4.0.
Features
15 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal fifth cranial nerve morphologyHPOHP:0010824
- Very frequent (80% to 99% of cases)
- Decreased corneal sensationHPOHP:0012155
- Very frequent (80% to 99% of cases)
- Slow decrease in visual acuityHPOHP:0007924
- Frequent (30% to 79% of cases)
- Anterior uveitisHPOHP:0012122
- Occasional (5% to 29% of cases)
- AstigmatismHPOHP:0000483
- Occasional (5% to 29% of cases)
- Blurred visionHPOHP:0000622
- Occasional (5% to 29% of cases)
- Corneal scarringHPOHP:0000559
- Occasional (5% to 29% of cases)
- Corneal stromal edemaHPOHP:0012040
- Occasional (5% to 29% of cases)
- Corneal ulcerationHPOHP:0012804
- Occasional (5% to 29% of cases)
- Diabetes mellitusHPOHP:0000819
- Occasional (5% to 29% of cases)
- Lacrimation abnormalityHPOHP:0000632
- Occasional (5% to 29% of cases)
- Recurrent corneal erosionsHPOHP:0000495
- Occasional (5% to 29% of cases)
Show the remaining 3
- AllodyniaHPOHP:0012533
- Very rare (1% to 4% of cases)
- Corneal perforationHPOHP:0100583
- Very rare (1% to 4% of cases)
- HyperesthesiaHPOHP:0100963
- Very rare (1% to 4% of cases)
Where it sits
- A kind of
Other names
1 name
Resolves to: neurotrophic keratopathy
- Also called
- neurotrophic keratitis