nephrotic syndrome, type 24
MONDO:0031008Mondo
Findings
No curated finding names nephrotic syndrome, type 24 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Juvenile onset · Childhood onset
HPO, annotations 2026-09-02
Features
27 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Focal segmental glomerulosclerosisHPOHP:0000097
- 4 of 4 reported patients
- Frequent (30% to 79% of cases)
- Podocyte foot process effacementHPOHP:0031266
- 4 of 4 reported patients
- Steroid-resistant nephrotic syndromeHPOHP:0012588
- 4 of 4 reported patients
- Abnormal circulating lipid concentrationHPOHP:0003119
- Very frequent (80% to 99% of cases)
- Abnormal glomerular visceral epithelial cell morphologyHPOHP:0031265
- Very frequent (80% to 99% of cases)
- HypoalbuminemiaHPOHP:0003073
- Very frequent (80% to 99% of cases)
- ProteinuriaHPOHP:0000093
- Very frequent (80% to 99% of cases)
- EdemaHPOHP:0000969
- Frequent (30% to 79% of cases)
- HypercholesterolemiaHPOHP:0003124
- Frequent (30% to 79% of cases)
- HypercoagulabilityHPOHP:0100724
- Frequent (30% to 79% of cases)
- HypertriglyceridemiaHPOHP:0002155
- Frequent (30% to 79% of cases)
- Minimal change glomerulonephritisHPOHP:0012579
- Frequent (30% to 79% of cases)
Show the remaining 15
- Abdominal painHPOHP:0002027
- Occasional (5% to 29% of cases)
- Abnormal urine outputHPOHP:0012590
- Occasional (5% to 29% of cases)
- Acute kidney injuryHPOHP:0001919
- Occasional (5% to 29% of cases)
- FeverHPOHP:0001945
- Occasional (5% to 29% of cases)
- Foamy urineHPOHP:0031504
- Occasional (5% to 29% of cases)
- HeadacheHPOHP:0002315
- Occasional (5% to 29% of cases)
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- DAAM2HGNC:18143
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal recessive · 2021
- Strong · PanelApp Australia · Autosomal recessive · 2025
Where it sits
- A kind of
Other names
3 names
Resolves to: nephrotic syndrome, type 24
- Also called
- idiopathic SRNSidiopathic steroid-resistant nephrotic syndromeNPHS24