myoclonic epilepsy in infancy
Findings
No curated finding names myoclonic epilepsy in infancy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A neonatal/infantile epilepsy syndrome that is characterized by the onset of myoclonic seizures between the ages of 6-18 months (range 4 months to 3 years). Males are twice as likely to be affected as females. Antecedent and birth history is unremarkable. Head size and neurological examination are normal. Prior development is usually normal. Cognitive, motor and behavioral difficulties are reported, especially if seizures are poorly controlled. Developmental outcome is normal in 60-85% of cases. Mild intellectual impairment and attention problems can be seen.
Definition from the Mondo Disease Ontology (MONDO:0100566), read 2026-09-29. CC BY 4.0.
Features
34 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Attention deficit hyperactivity disorderHPOHP:0007018
- Very frequent (80% to 99% of cases)
- Bilateral tonic-clonic seizureHPOHP:0002069
- Very frequent (80% to 99% of cases)
- EEG with irregular generalized spike and wave complexesHPOHP:0001326
- Very frequent (80% to 99% of cases)
- Generalized myoclonic seizureHPOHP:0002123
- Very frequent (80% to 99% of cases)
- Mild intellectual disabilityHPOHP:0001256
- Very frequent (80% to 99% of cases)
- SeizureHPOHP:0001250
- Very frequent (80% to 99% of cases)
Show the remaining 22
- IncoordinationHPOHP:0002311
- Frequent (30% to 79% of cases)
- Interictal EEG abnormalityHPOHP:0025373
- Frequent (30% to 79% of cases)
- IrritabilityHPOHP:0000737
- Frequent (30% to 79% of cases)
- Mental deteriorationHPOHP:0001268
- Frequent (30% to 79% of cases)
- MyoclonusHPOHP:0001336
- Frequent (30% to 79% of cases)
- Poor hand-eye coordinationHPOHP:0007057
- Frequent (30% to 79% of cases)
Where it sits
Other names
3 names
Resolves to: myoclonic epilepsy in infancy
- Also called
- benign myoclonic epilepsy of infancybenign myoclonus epilepsy of infancyMEI