myeloid neoplasm associated with PDGFRB rearrangement
Findings
No curated finding names myeloid neoplasm associated with PDGFRB rearrangement yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare, malignant, neoplastic disease characterized by clonal proliferation of myeloid and/or lymphoid precursors harboring rearrangements in the PDGFRB gene, in the blood, bone marrow and often other tissues as well (spleen, lymph nodes, skin, etc.). It usually presents as chronic myelomonocytic leukemia with eosinophilia, chronic eosinophilic leukemia, atypical chronic myelogenous leukemia, juvenile myelomonocytic leukemia, myelodysplastic syndrome, acute myeloid leukemia or acute lymphoblastic leukemia. Patients usually present with anemia, leukocytosis, monocytosis, eosinophilia and/or splenomegaly, or systemic symptoms, such as fever, sweating and/or weight loss.
Definition from the Mondo Disease Ontology (MONDO:0015690), read 2026-09-29. CC BY 4.0.
Where it sits
Other names
4 names
Resolves to: myeloid neoplasm associated with PDGFRB rearrangement
- Also called
- myeloid and lymphoid neoplasms with PDGFRB rearrangementmyeloid neoplasms associated with PDGFRB rearrangementmyeloid neoplasms with PDGFRB rearrangementmyeloid/lymphoid neoplasms with PDGFRB rearrangement