myasthenia gravis
MONDO:0009688Mondo
Findings
No curated finding names myasthenia gravis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Myasthenia gravis (MG) is a rare, clinically heterogeneous, autoimmune disorder of the neuromuscular junction characterized by fatigable weakness of voluntary muscles.
Definition from the Mondo Disease Ontology (MONDO:0009688), read 2026-09-29. CC BY 4.0.
Features
45 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Muscle weaknessHPOHP:0001324
- Very frequent (80% to 99% of cases)
- Abnormal thymus morphologyHPOHP:0000777
- Frequent (30% to 79% of cases)
- Anti-DCC netrin 1 receptor antibody positivityHPOHP:6000881
- Frequent (30% to 79% of cases)
- Anti-Kv1.4 antibodyHPOHP:5000048
- Frequent (30% to 79% of cases)
- Anti-muscle-specific tyrosine kinase antibodyHPOHP:0030210
- Frequent (30% to 79% of cases)
- Anti-neuromuscular Junction acetylcholine receptor antibody positivityHPOHP:0030208
- Frequent (30% to 79% of cases)
- Anti-ryanodine receptor antibodyHPOHP:5000047
- Frequent (30% to 79% of cases)
- Anti-titin antibody positivityHPOHP:5000038
- Frequent (30% to 79% of cases)
- Bulbar palsyHPOHP:0001283
- Frequent (30% to 79% of cases)
- Difficulty climbing stairsHPOHP:0003551
- Frequent (30% to 79% of cases)
- DiplopiaHPOHP:0000651
- Frequent (30% to 79% of cases)
- DysarthriaHPOHP:0001260
- Frequent (30% to 79% of cases)
Show the remaining 33
- DysphagiaHPOHP:0002015
- Frequent (30% to 79% of cases)
- DysphoniaHPOHP:0001618
- Frequent (30% to 79% of cases)
- DyspneaHPOHP:0002094
- Frequent (30% to 79% of cases)
- Fatigable weakness of skeletal musclesHPOHP:0030197
- Frequent (30% to 79% of cases)
- FatigueHPOHP:0012378
- Frequent (30% to 79% of cases)
- Limb muscle weaknessHPOHP:0003690
- Frequent (30% to 79% of cases)
Where it sits
- Narrower terms (11)
- AChR+ myasthenia gravis
- adult-onset myasthenia gravis
- generalized myasthenia gravis
- juvenile myasthenia gravis
- muscle-specific tyrosine kinase-associated myasthenia gravis
- myasthenia gravis with thymus hyperplasia
- myasthenia, limb-girdle, autoimmune
- neonatal myasthenia gravis
- ocular myasthenia gravis
- seronegative myasthenia gravis
- transient neonatal myasthenia gravis
Other names
2 names
Resolves to: myasthenia gravis
- Also called
- acquired myastheniaautoimmune myasthenia gravis