multicentric reticulohistiocytosis
MONDO:0015347Mondo
Findings
No curated finding names multicentric reticulohistiocytosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Multicentric reticulohistiocytosis (MRH) is a rare non-Langerhans cell histiocytosis characterized by the association of specific nodular skin lesions and destructive arthritis.
Definition from the Mondo Disease Ontology (MONDO:0015347), read 2026-09-29. CC BY 4.0.
Features
6 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- ArthritisHPOHP:0001369
- Very frequent (80% to 99% of cases)
- HistiocytosisHPOHP:0100727
- Very frequent (80% to 99% of cases)
- Skin noduleHPOHP:0200036
- Very frequent (80% to 99% of cases)
- CachexiaHPOHP:0004326
- Occasional (5% to 29% of cases)
- FeverHPOHP:0001945
- Occasional (5% to 29% of cases)
- Muscle weaknessHPOHP:0001324
- Occasional (5% to 29% of cases)
Where it sits
Other names
2 names
Resolves to: multicentric reticulohistiocytosis
- Also called
- giant cell histiocytomatosislipoid dermatoarthritis