mueller-weiss syndrome
Findings
No curated finding names mueller-weiss syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare bone disease characterized by spontaneous adult-onset tarsal navicular osteonecrosis. Patients present with chronic mid- and hindfoot pain, swelling and tenderness over the dorsomedial aspect of the midfoot, flattening of the medial longitudinal arch, and pes planovarus. Radiographic findings include comma-shaped deformity due to collapse of the lateral part of the navicular bone and medial or dorsal protrusion of a portion or the entire bone. The condition may be bilateral or asymmetric and associated with pathological fractures.
Definition from the Mondo Disease Ontology (MONDO:0035452), read 2026-09-29. CC BY 4.0.
Features
21 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Foot painHPOHP:0025238
- Very frequent (80% to 99% of cases)
- Abnormality of the os naviculare pedisHPOHP:0100339
- Frequent (30% to 79% of cases)
- Avascular necrosisHPOHP:0010885
- Frequent (30% to 79% of cases)
- ChondritisHPOHP:0100662
- Frequent (30% to 79% of cases)
- Edema of the dorsum of feetHPOHP:0012098
- Frequent (30% to 79% of cases)
- Facet joint arthrosisHPOHP:0030871
- Frequent (30% to 79% of cases)
- Gait disturbance
Show the remaining 9
- ArthritisHPOHP:0001369
- Occasional (5% to 29% of cases)
- Equinovarus deformityHPOHP:0008110
- Occasional (5% to 29% of cases)
- Fragmented, irregular epiphysesHPOHP:0005063
- Occasional (5% to 29% of cases)
- Joint subluxationHPOHP:0032153
- Occasional (5% to 29% of cases)
- Knee osteoarthritisHPOHP:0005086
- Occasional (5% to 29% of cases)
- Pes planusHPOHP:0001763
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
2 names
Resolves to: mueller-weiss syndrome
- Also called
- Brailsford diseaseMueller-Weiss osteonecrosis of the tarsal bone