Miller Fisher syndrome
MONDO:0005851Mondo
Findings
No curated finding names Miller Fisher syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An autoimmune process characterized by the clinical triad of ophthalmoplegia, ataxia, and areflexia.
Definition from the Mondo Disease Ontology (MONDO:0005851), read 2026-09-29. CC BY 4.0.
Features
26 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Anti-GQ1b antibody positivityHPOHP:0034122
- Very frequent (80% to 99% of cases)
- AreflexiaHPOHP:0001284
- Very frequent (80% to 99% of cases)
- External ophthalmoplegiaHPOHP:0000544
- Very frequent (80% to 99% of cases)
- AtaxiaHPOHP:0001251
- Frequent (30% to 79% of cases)
- DiplopiaHPOHP:0000651
- Frequent (30% to 79% of cases)
- EEG with generalized slow activityHPOHP:0010845
- Frequent (30% to 79% of cases)
- EMG abnormalityHPOHP:0003457
- Frequent (30% to 79% of cases)
- Horizontal nystagmusHPOHP:0000666
- Frequent (30% to 79% of cases)
- Increased CSF protein concentrationHPOHP:0002922
- Frequent (30% to 79% of cases)
- Internal ophthalmoplegiaHPOHP:0007942
- Frequent (30% to 79% of cases)
- MydriasisHPOHP:0011499
- Frequent (30% to 79% of cases)
- Abnormality of ocular abductionHPOHP:0011347
- Occasional (5% to 29% of cases)
Show the remaining 14
- AnisocoriaHPOHP:0009916
- Occasional (5% to 29% of cases)
- Blurred visionHPOHP:0000622
- Occasional (5% to 29% of cases)
- Bulbar palsyHPOHP:0001283
- Occasional (5% to 29% of cases)
- CSF pleocytosisHPOHP:0012229
- Occasional (5% to 29% of cases)
- Facial palsyHPOHP:0010628
- Occasional (5% to 29% of cases)
- FeverHPOHP:0001945
- Occasional (5% to 29% of cases)
Where it sits
Other names
12 names
Resolves to: Miller Fisher syndrome
- Also called
- cranial variant of GBScranial variant of Guillain-Barre syndromecranial variant of Guillain-Barré syndromeFisher syndromeGuillain Barre syndrome, Miller Fisher variantGuillain-Barre syndrome, Miller Fisher variantMiller Fisher variant of Guillain Barre syndromeMiller-Fisher syndromeophthalmoplegia, ataxia and areflexia syndromesyndrome, Fishersyndrome, Miller Fishersyndrome, Miller-Fisher