migraine, familial hemiplegic, 3
Findings
No curated finding names migraine, familial hemiplegic, 3 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any familial or sporadic hemiplegic migraine in which the cause of the disease is a mutation in the SCN1A gene.
Definition from the Mondo Disease Ontology (MONDO:0012320), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Juvenile onset · Young adult onset
HPO, annotations 2026-09-02
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- PhonophobiaHPOHP:0002183
- 16 of 17 reported patients
- PhotophobiaHPOHP:0000613
- 16 of 18 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- SCN1AHGNC:10585
- Strong · Ambry Genetics · Autosomal dominant · 2015
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2023
Where it sits
- A kind of
Other names
3 names
Resolves to: migraine, familial hemiplegic, 3
- Also called
- familial or sporadic hemiplegic migraine caused by mutation in SCN1Amigraine, familial hemiplegic, type 3SCN1A familial or sporadic hemiplegic migraine