microform holoprosencephaly
MONDO:0017219Mondo
Findings
No curated finding names microform holoprosencephaly yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Microform holoprosencephaly is a benign form of holoprosencephaly (HPE) characterized by midline defects without the typical HPE defect in brain cleavage.
Definition from the Mondo Disease Ontology (MONDO:0017219), read 2026-09-29. CC BY 4.0.
Features
34 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Choanal atresiaHPOHP:0000453
- Very frequent (80% to 99% of cases)
- Midnasal stenosisHPOHP:0010644
- Very frequent (80% to 99% of cases)
- Solitary median maxillary central incisorHPOHP:0006315
- Very frequent (80% to 99% of cases)
- HypotelorismHPOHP:0000601
- Frequent (30% to 79% of cases)
- Intellectual disabilityHPOHP:0001249
- Frequent (30% to 79% of cases)
- Intrauterine growth retardationHPOHP:0001511
- Frequent (30% to 79% of cases)
- MicrocephalyHPOHP:0000252
- Frequent (30% to 79% of cases)
- Narrow nasal bridgeHPOHP:0000446
- Frequent (30% to 79% of cases)
- Premature birthHPOHP:0001622
- Frequent (30% to 79% of cases)
- Short philtrumHPOHP:0000322
- Frequent (30% to 79% of cases)
- Short statureHPOHP:0004322
- Frequent (30% to 79% of cases)
- Tented upper lip vermilionHPOHP:0010804
- Frequent (30% to 79% of cases)
Show the remaining 22
- Abnormal cardiovascular system morphologyHPOHP:0030680
- Occasional (5% to 29% of cases)
- Agenesis of corpus callosumHPOHP:0001274
- Occasional (5% to 29% of cases)
- Ambiguous genitaliaHPOHP:0000062
- Occasional (5% to 29% of cases)
- Anteverted naresHPOHP:0000463
- Occasional (5% to 29% of cases)
- AsthmaHPOHP:0002099
- Occasional (5% to 29% of cases)
- Cleft palateHPOHP:0000175
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
6 names
Resolves to: microform holoprosencephaly
- Also called
- HoloprosencC)phalie, minor formHoloprosencéphalie, minor formholoprosencephaly-likeHPE-LHPE, minor formMicroform HPE