methanol poisoning
Findings
No curated finding names methanol poisoning yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Methanol poisoning is a rare poisoning resulting in elevated anion gap metabolic acidosis, due to the alcohol dehydrogenase (ADH)-mediated production of formic acid (which is poisonous to the central nervous system), and characterized by dizziness, nausea, vomiting, confusion, metabolic acidosis, visual disturbances (which if left untreated can lead to blindness), coma, and death (due to respiratory failure).
Definition from the Mondo Disease Ontology (MONDO:0017860), read 2026-09-29. CC BY 4.0.
Features
29 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Metabolic acidosisHPOHP:0001942
- Very frequent (80% to 99% of cases)
- Abnormal putamen morphologyHPOHP:0031982
- Frequent (30% to 79% of cases)
- Addictive alcohol useHPOHP:0030955
- Frequent (30% to 79% of cases)
- Blurred visionHPOHP:0000622
- Frequent (30% to 79% of cases)
- HyperlipidemiaHPOHP:0003077
- Frequent (30% to 79% of cases)
- HypertensionHPOHP:0000822
- Frequent (30% to 79% of cases)
- Intracranial hemorrhage
Show the remaining 17
- Abnormal optic nerve morphologyHPOHP:0000587
- Occasional (5% to 29% of cases)
- Basal ganglia necrosisHPOHP:0012128
- Occasional (5% to 29% of cases)
- Bilateral basal ganglia lesionsHPOHP:0007146
- Occasional (5% to 29% of cases)
- BlindnessHPOHP:0000618
- Occasional (5% to 29% of cases)
- ComaHPOHP:0001259
- Occasional (5% to 29% of cases)
- ConfusionHPOHP:0001289
- Occasional (5% to 29% of cases)
Where it sits
- A kind of