metabolic dysfunction-associated steatotic liver disease
Findings
No curated finding names metabolic dysfunction-associated steatotic liver disease yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as nonalcoholic fatty liver disease or NAFLD) is a type of liver disease that is not caused by alcohol. It typically does not cause symptoms in the early stages, but it can cause health problems due to fat accumulation, inflammation, and scarring in the liver.
Definition from the Mondo Disease Ontology (MONDO:0013209), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- PNPLA3HGNC:18590
- Limited · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- A kind of
- Narrower terms (2)
Other names
7 names
Resolves to: metabolic dysfunction-associated steatotic liver disease
- Also called
- fatty liver disease, nonalcoholicMASLDNAFLDNAFLD - nonalcoholic fatty liver diseasenon-alcoholic fatty livernon-alcoholic fatty liver diseasenonalcoholic fatty liver disease