melanoma, cutaneous malignant, susceptibility to, 2
Findings
No curated finding names melanoma, cutaneous malignant, susceptibility to, 2 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Clinically atypical nevi (usually exceeding 5 mm in diameter and having variable pigmentation and ill defined borders) with an increased risk for development of non-familial cutaneous malignant melanoma. Biopsies show melanocytic dysplasia. Nevi are clinically and histologically identical to the precursor lesions for melanoma in the B-K mole syndrome. (Stedman, 25th ed)
Definition from the Mondo Disease Ontology (MONDO:0007964), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- HGNC:1787HGNC:1787
- Definitive · G2P · Autosomal dominant · 2017
Where it sits
Other names
6 names
Resolves to: melanoma, cutaneous malignant, susceptibility to, 2
- Also called
- Atypical Mole syndromeB-K Mole syndromedysplastic nevus syndromefamilial dysplastic nevimelanoma, cutaneous malignant, 2melanoma, cutaneous malignant, susceptibility to, type 2