MCD diffuse large B-cell lymphoma
MONDO:0850470Mondo
Findings
No curated finding names MCD diffuse large B-cell lymphoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A diffuse large B-cell lymphoma that is categorized as MCD with high probability by the LymphGen algorithm. This is based on a combination of genetic features and MCD DLBCLs often, but do not always, have the most common hot spot mutation in MYD88 (L265P) and/or activating mutations in CD79B. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting PIM1 and/or ETV6, which can be coding or non-coding.
Definition from the Mondo Disease Ontology (MONDO:0850470), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of