maturity-onset diabetes of the young type 6
Findings
No curated finding names maturity-onset diabetes of the young type 6 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Monogenic diabetes caused by inactivating mutation(s) in the gene NEUROD1, encoding neurogenic differentiation 1. In addition to diabetes, this condition may be associated with neurogenic anomalies. Homozygous NEUROD1 mutations result in permanent neonatal diabetes.
Definition from the Mondo Disease Ontology (MONDO:0011668), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
1 feature
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Maturity-onset diabetes of the youngHPOHP:0004904
- Young adult onset
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- NEUROD1HGNC:7762
- Strong · Genomics England PanelApp · Autosomal recessive · 2020
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2023
- Strong · PanelApp Australia · Autosomal dominant · 2025
- Strong · PanelApp Australia · Autosomal recessive · 2025
- Moderate · Ambry Genetics · Autosomal dominant · 2023
Where it sits
- A kind of
Other names
7 names
Resolves to: maturity-onset diabetes of the young type 6
- Also called
- maturity onset diabetes of the Young, type 6maturity-onset diabetes of the young (disease) caused by mutation in NEUROD1maturity-onset diabetes of the young 6MODY6NEUROD1 maturity-onset diabetes of the young (disease)NEUROD1-associated monogenic diabetesneurogenic differentiation Factor 1-associated monogenic diabetes