mast cell activation syndrome
MONDO:0100004Mondo
Findings
No curated finding names mast cell activation syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A clinically defined disease states with a largely unknown morphological background. Acute mast cell activation (MCA) is commonly seen in allergic reactions and often leads to the clinical signs and symptoms of anaphylaxis. Severe or even life‐threatening MCA may occur when the burden of mast cells is high and/or these cells are in an hyperactivated state. Mastocytosis may be associated with mast cell activation syndrome (MCAS).
Definition from the Mondo Disease Ontology (MONDO:0100004), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
3 names
Resolves to: mast cell activation syndrome
- Also called
- disorder of mast cell activationMACSmast cell activation disease