malignant atrophic papulosis
Findings
No curated finding names malignant atrophic papulosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Malignant atrophic papulosis (MAP) is a rare, chronic, thrombo-obliterative vasculopathy characterized by papular skin lesions with central porcelain-white atrophy and a surrounding teleangiectatic rim. Systemic lesions may affect the gastrointestinal tract and the central nervous system (CNS) and are potentially lethal.
Definition from the Mondo Disease Ontology (MONDO:0011208), read 2026-09-29. CC BY 4.0.
Features
35 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Dermal atrophyHPOHP:0004334
- Very frequent (80% to 99% of cases)
- PapuleHPOHP:0200034
- Very frequent (80% to 99% of cases)
- Telangiectasia of the skinHPOHP:0100585
- Very frequent (80% to 99% of cases)
- Abdominal painHPOHP:0002027
- Frequent (30% to 79% of cases)
- FatigueHPOHP:0012378
- Frequent (30% to 79% of cases)
- Gastrointestinal hemorrhageHPOHP:0002239
- Frequent (30% to 79% of cases)
- Gastrointestinal infarctionsHPOHP:0005244
- Frequent (30% to 79% of cases)
- Intestinal perforationHPOHP:0031368
- Frequent (30% to 79% of cases)
- Muscle flaccidityHPOHP:0010547
- Frequent (30% to 79% of cases)
- Nausea and vomitingHPOHP:0002017
- Frequent (30% to 79% of cases)
- Weight lossHPOHP:0001824
- Frequent (30% to 79% of cases)
- Abnormal myocardium morphologyHPOHP:0001637
- Occasional (5% to 29% of cases)
Show the remaining 23
- Abnormal optic nerve morphologyHPOHP:0000587
- Occasional (5% to 29% of cases)
- Abnormal pericardium morphologyHPOHP:0001697
- Occasional (5% to 29% of cases)
- Abnormality of the lower urinary tractHPOHP:0010936
- Occasional (5% to 29% of cases)
- Amaurosis fugaxHPOHP:0100576
- Occasional (5% to 29% of cases)
- Arterial thrombosisHPOHP:0004420
- Occasional (5% to 29% of cases)
- ArteritisHPOHP:0012089
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
6 names
Resolves to: malignant atrophic papulosis
- Also called
- Degos DiseaseKohlmeier-Degos diseaseKöhlmeier-Degos diseaseKohlmeier-Degos-Delort-Tricort syndromeKöhlmeier-Degos-Delort-Tricort syndromepapulosis atrophican maligna