Madras motor neuron disease
MONDO:0015307Mondo
Findings
No curated finding names Madras motor neuron disease yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Madras motor neuron disease (MMND) is characterized by weakness and atrophy of limbs, multiple lower cranial nerve palsies and sensorineural hearing loss.
Definition from the Mondo Disease Ontology (MONDO:0015307), read 2026-09-29. CC BY 4.0.
Features
17 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Bulbar palsyHPOHP:0001283
- Very frequent (80% to 99% of cases)
- Sensorineural hearing impairmentHPOHP:0000407
- Very frequent (80% to 99% of cases)
- Babinski signHPOHP:0003487
- Frequent (30% to 79% of cases)
- Distal amyotrophyHPOHP:0003693
- Frequent (30% to 79% of cases)
- Distal muscle weaknessHPOHP:0002460
- Frequent (30% to 79% of cases)
- Hyperactive deep tendon reflexesHPOHP:0006801
- Frequent (30% to 79% of cases)
- Limb fasciculationsHPOHP:0007289
- Frequent (30% to 79% of cases)
- Weak voiceHPOHP:0001621
- Frequent (30% to 79% of cases)
- Abnormal cerebellum morphologyHPOHP:0001317
- Occasional (5% to 29% of cases)
- Diminished deep tendon reflexHPOHP:0001315
- Occasional (5% to 29% of cases)
- DysphagiaHPOHP:0002015
- Occasional (5% to 29% of cases)
- Optic atrophyHPOHP:0000648
- Occasional (5% to 29% of cases)
Show the remaining 5
- SchizophreniaHPOHP:0100753
- Occasional (5% to 29% of cases)
- TinnitusHPOHP:0000360
- Occasional (5% to 29% of cases)
- Visual impairmentHPOHP:0000505
- Occasional (5% to 29% of cases)
- Facial palsyHPOHP:0010628
- Very rare (1% to 4% of cases)
- Reduced visual acuityHPOHP:0007663
- Very rare (1% to 4% of cases)
Where it sits
- A kind of
Other names
1 name
Resolves to: Madras motor neuron disease
- Also called
- MMND