Lynch syndrome 8
MONDO:0013196Mondo
Findings
No curated finding names Lynch syndrome 8 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Late onset · Middle age onset · Late young adult onset
HPO, annotations 2026-09-02
Features
4 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Colon cancerHPOHP:0003003
- 2 of 10 reported patients
- Endometrial carcinomaHPOHP:0012114
- 1 of 9 reported patients
- Adenomatous colonic polyposisHPOHP:0005227
- 1 of 10 reported patients
- Hereditary nonpolyposis colorectal carcinomaHPOHP:0006716
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- EPCAMHGNC:11529
- Definitive · Ambry Genetics · Autosomal dominant · 2019
- Definitive · G2P · Autosomal dominant · 2023
- Strong · Genomics England PanelApp · Autosomal dominant · 2020
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2022
Where it sits
- A kind of
Other names
3 names
Resolves to: Lynch syndrome 8
- Also called
- colorectal cancer, hereditary nonpolyposis, type 8EPCAM hereditary nonpolyposis colon cancerhereditary nonpolyposis colon cancer caused by mutation in EPCAM