liver neuroendocrine carcinoma
MONDO:0015072Mondo
Findings
No curated finding names liver neuroendocrine carcinoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An extremely rare, aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the liver.
Definition from the Mondo Disease Ontology (MONDO:0015072), read 2026-09-29. CC BY 4.0.
Features
36 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Neoplasm of the liverHPOHP:0002896
- Obligate (100% of cases)
- Neuroendocrine neoplasmHPOHP:0100634
- Obligate (100% of cases)
- Abdominal distentionHPOHP:0003270
- Frequent (30% to 79% of cases)
- AnorexiaHPOHP:0002039
- Frequent (30% to 79% of cases)
- AscitesHPOHP:0001541
- Frequent (30% to 79% of cases)
- Chronic fatigueHPOHP:0012432
- Frequent (30% to 79% of cases)
- Chronic noninfectious lymphadenopathyHPOHP:0002730
- Frequent (30% to 79% of cases)
- DiarrheaHPOHP:0002014
- Frequent (30% to 79% of cases)
- DyspneaHPOHP:0002094
- Frequent (30% to 79% of cases)
- Elevated circulating hepatic transaminase concentrationHPOHP:0002910
- Frequent (30% to 79% of cases)
- Episodic abdominal painHPOHP:0002574
- Frequent (30% to 79% of cases)
- HepatomegalyHPOHP:0002240
- Frequent (30% to 79% of cases)
Reported absent (2)
- Elevated circulating alpha-fetoprotein concentrationHPOHP:0006254
- Elevated circulating CEA concentrationHPOHP:0031029
Show the remaining 24
- NauseaHPOHP:0002018
- Frequent (30% to 79% of cases)
- Weight lossHPOHP:0001824
- Frequent (30% to 79% of cases)
- BronchoconstrictionHPOHP:4000007
- Occasional (5% to 29% of cases)
- Carcinoid tumorHPOHP:0100570
- Occasional (5% to 29% of cases)
- Erythematous plaqueHPOHP:0025474
- Occasional (5% to 29% of cases)
- Facial telangiectasiaHPOHP:0007380
- Occasional (5% to 29% of cases)
Where it sits
Other names
7 names
Resolves to: liver neuroendocrine carcinoma
- Also called
- hepatic neuroendocrine carcinomaHNECliver neuroendocrine cancerneuroendocrine carcinoma of liverPHNECprimary hepatic neuroendocrine carcinomaprimary liver neuroendocrine carcinoma