Lisch epithelial corneal dystrophy
Findings
No curated finding names Lisch epithelial corneal dystrophy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Lisch epithelial corneal dystrophy (LECD) is a very rare form of superficial corneal dystrophy characterized by feather-shaped opacities and microcysts in the corneal epithelium arranged in a band-shaped and sometimes whorled pattern, occasionally with impaired vision.
Definition from the Mondo Disease Ontology (MONDO:0010425), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Childhood onset
HPO, annotations 2026-09-02
Features
1 feature
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Band-shaped corneal dystrophyHPOHP:0007709
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- MCOLN1HGNC:13356
- Strong · PanelApp Australia · Autosomal dominant · 2025
- Limited · Ambry Genetics · Autosomal dominant · 2024
Where it sits
Other names
3 names
Resolves to: Lisch epithelial corneal dystrophy
- Also called
- band-shaped and whorled microcystic dystrophy of the corneal epitheliumcorneal dystrophy, Lisch epithelial, X-linked dominantLECD