linear IgA Dermatosis
Findings
No curated finding names linear IgA Dermatosis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Autoimmune disease characterized by subepidermal blisters and linear deposition of autoantibodies at the dermoepidermal junction. The accumulated autoantibodies are of immunoglobulin A and occasionally immunoglobulin G classes against epidermal basement membrane proteins. The dermatosis is sometimes associated with malignancies and use of certain drugs (e.g., vancomycin).
Definition from the Mondo Disease Ontology (MONDO:0018748), read 2026-09-29. CC BY 4.0.
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal blistering of the skinHPOHP:0008066
- Very frequent (80% to 99% of cases)
- AutoimmunityHPOHP:0002960
- Very frequent (80% to 99% of cases)
- PapuleHPOHP:0200034
- Very frequent (80% to 99% of cases)
- Anti-LABD97 antibody positivityHPOHP:4000028
- Frequent (30% to 79% of cases)
- Anti-LAD-1 antibody positivityHPOHP:4000027
- Frequent (30% to 79% of cases)
- Oral ulcerHPOHP:0000155
- Frequent (30% to 79% of cases)
- Bladder neoplasm
Where it sits
- A kind of