limbic encephalitis with LGI1 antibodies
Findings
No curated finding names limbic encephalitis with LGI1 antibodies yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Limbic encephalitis with LGI1 antibodies is a rare neuroimmunological disorder characterized by the onset of cognitive decline, psychiatric disturbances and seizures (distinctively faciobrachial dystonic seizures) in association with detection of LGI1 antibodies in serum or cerebrospinal fluid. Patients may present with confusion, hallucinations, vocalization, paranoia, tangentiality, aggressive outbursts and/or spatial disorientation, as well as obstinate hyponatremia. It is most often non-paraneoplastic, however comorbid tumors, such as small cell lung cancer and thymoma, have been reported.
Definition from the Mondo Disease Ontology (MONDO:0015592), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
1 name
Resolves to: limbic encephalitis with LGI1 antibodies
- Also called
- limbic encephalitis with leucine-rich glioma-inactivated 1 antibodies