leukoencephalopathy without lacunae, adult-onset
MONDO:0980752Mondo
Findings
No curated finding names leukoencephalopathy without lacunae, adult-onset yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Late onset · Middle age onset · Young adult onset
HPO, annotations 2026-09-02
Features
30 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal circulating lipid concentrationHPOHP:0003119
- 1 of 1 reported patient
- Anomic aphasiaHPOHP:0030784
- 2 of 2 reported patients
- Anterograde memory impairmentHPOHP:0033689
- 5 of 5 reported patients
- ApathyHPOHP:0000741
- 2 of 2 reported patients
- Bilateral tonic-clonic seizure with generalized onsetHPOHP:0025190
- 1 of 1 reported patient
- Cerebral hemorrhageHPOHP:0001342
- 1 of 1 reported patient
- ConfusionHPOHP:0001289
- 1 of 1 reported patient
- DepressionHPOHP:0000716
- 1 of 1 reported patient
- DysarthriaHPOHP:0001260
- 1 of 1 reported patient
- Hyperintensity of cerebral white matter on MRIHPOHP:0030890
- 6 of 6 reported patients
- Hypertensive retinopathyHPOHP:0001095
- 1 of 1 reported patient
- HypoesthesiaHPOHP:0033748
- 1 of 1 reported patient
Show the remaining 18
- Impaired executive functioningHPOHP:0033051
- 3 of 3 reported patients
- Intention tremorHPOHP:0002080
- 1 of 1 reported patient
- Lack of insightHPOHP:0000757
- 4 of 4 reported patients
- Migraine without auraHPOHP:0002083
- 1 of 1 reported patient
- ParesthesiaHPOHP:0003401
- 1 of 1 reported patient
- Postural instabilityHPOHP:0002172
- 1 of 1 reported patient
Where it sits
- A kind of