lethal Larsen-like syndrome
MONDO:0009512Mondo
Findings
No curated finding names lethal Larsen-like syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Larsen-like syndrome, lethal type, is characterized by multiple joint dislocation and respiratory insufficiency due to tracheomalacia and/or lung hypoplasia. It has been described in less than ten patients. Transmission is thought to be autosomal recessive. Brain dysplasia has been described in some patients and could result from systemic hypoxic-ischemic insults during the second half of pregnancy, although genetic factors have not been ruled out.
Definition from the Mondo Disease Ontology (MONDO:0009512), read 2026-09-29. CC BY 4.0.