laryngotracheoesophageal cleft
MONDO:0016060Mondo
Findings
No curated finding names laryngotracheoesophageal cleft yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A laryngo-tracheo-esophageal cleft (LC) is a congenital malformation characterized by an abnormal, posterior, sagittal communication between the larynx and the pharynx, possibly extending downward between the trachea and the esophagus.
Definition from the Mondo Disease Ontology (MONDO:0016060), read 2026-09-29. CC BY 4.0.
Features
13 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Laryngeal cleftHPOHP:0008751
- Obligate (100% of cases)
- Abnormality of the voiceHPOHP:0001608
- Frequent (30% to 79% of cases)
- AspirationHPOHP:0002835
- Frequent (30% to 79% of cases)
- Choking episodesHPOHP:0030842
- Frequent (30% to 79% of cases)
- CoughHPOHP:0012735
- Frequent (30% to 79% of cases)
- CyanosisHPOHP:0000961
- Frequent (30% to 79% of cases)
- DyspneaHPOHP:0002094
- Frequent (30% to 79% of cases)
- Hoarse cryHPOHP:0001615
- Frequent (30% to 79% of cases)
- Impaired oropharyngeal swallow responseHPOHP:0031162
- Frequent (30% to 79% of cases)
- LaryngomalaciaHPOHP:0001601
- Frequent (30% to 79% of cases)
- Recurrent respiratory infectionsHPOHP:0002205
- Frequent (30% to 79% of cases)
- StridorHPOHP:0010307
- Frequent (30% to 79% of cases)
Show the remaining 1
- Neonatal respiratory distressHPOHP:0002643
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
8 names
Resolves to: laryngotracheoesophageal cleft
- Also called
- congenital cleft larynxLarnygeotracheoesophageal cleftlaryngeal cleftlaryngo-tracheo-esophageal cleftlaryngo-tracheo-esophageal diastemaLCLTECtracheal cleft