large cell neuroendocrine carcinoma
MONDO:0005057Mondo
Findings
No curated finding names large cell neuroendocrine carcinoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A usually aggressive carcinoma composed of large malignant cells which display neuroendocrine characteristics. It is characterized by the presence of high mitotic activity and necrotic changes. The vast majority of cases are positive for neuron-specific enolase. Representative examples include lung, breast, cervical, and thymic neuroendocrine carcinomas.
Definition from the Mondo Disease Ontology (MONDO:0005057), read 2026-09-29. CC BY 4.0.
Where it sits
Other names
3 names
Resolves to: large cell neuroendocrine carcinoma
- Also called
- large cell NEClarge-cell neuroendocrine carcinomaLCNEC