language delay and attention deficit-hyperactivity disorder/cognitive impairment with or without cardiac arrhythmia
Findings
No curated finding names language delay and attention deficit-hyperactivity disorder/cognitive impairment with or without cardiac arrhythmia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Infantile onset
HPO, annotations 2026-09-02
Features
16 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- BradycardiaHPOHP:0001662
- 6 of 6 reported patients
- Delayed speech and language developmentHPOHP:0000750
- 13 of 13 reported patients
- HyperactivityHPOHP:0000752
- 4 of 4 reported patients
- Sick sinus syndromeHPOHP:0011704
- 9 of 9 reported patients
- NystagmusHPOHP:0000639
- 6 of 7 reported patients
- Attention deficit hyperactivity disorderHPOHP:0007018
- 3 of 4 reported patients
- Intellectual disabilityHPOHP:0001249
- 9 of 13 reported patients
- HypotoniaHPOHP:0001252
- 6 of 9 reported patients
- Gastroesophageal refluxHPOHP:0002020
- 5 of 8 reported patients
- Motor delayHPOHP:0001270
- 3 of 5 reported patients
- SeizureHPOHP:0001250
- 4 of 9 reported patients
- Absent speechHPOHP:0001344
- 2 of 5 reported patients
Show the remaining 4
- Patent foramen ovaleHPOHP:0001655
- 1 of 8 reported patients
- Poor fine motor coordinationHPOHP:0007010
- 1 of 9 reported patients
- MicrocephalyHPOHP:0000252
- 0 of 3 reported patients
- Global developmental delayHPOHP:0001263
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- GNB5HGNC:4401
- Strong · Ambry Genetics · Autosomal recessive · 2020
Where it sits
- A kind of
Other names
3 names
Resolves to: language delay and attention deficit-hyperactivity disorder/cognitive impairment with or without cardiac arrhythmia
- Also called
- LADCIlanguage delay and ADHD/cognitive impairment with or without cardiac arrhythmialanguage delay and attention deficit-hyperactivity disorder/cognitive impairment with or without cardiac arrhythmia; LADCI