Kimura disease
Findings
No curated finding names Kimura disease yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Kimura disease is a benign and chronic inflammatory disorder of unknown etiology, occurring mainly in Asian countries (very rarely in Western countries) and predominantly affecting young men, that usually presents with a solitary or multiple non-tender subcutaneous masses in the head and neck region (in particular the preauricular and submandibular area) and/or generalized painless lymphadenopathy, often with salivary gland involvement. Characteristic laboratory findings include blood eosinophilia and markedly elevated serum immunoglobulin E (IgE) levels. It is often associated with autoinflammatory disorders (i.e. ulcerative colitis, bronchial asthma) and a co-existing renal disease.
Definition from the Mondo Disease Ontology (MONDO:0018830), read 2026-09-29. CC BY 4.0.
Features
5 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Follicular hyperplasiaHPOHP:0002729
- Very frequent (80% to 99% of cases)
- Increased circulating IgE concentrationHPOHP:0003212
- Very frequent (80% to 99% of cases)
- Increased total eosinophil countHPOHP:0001880
- Very frequent (80% to 99% of cases)
- LymphadenopathyHPOHP:0002716
- Frequent (30% to 79% of cases)
- Abnormal salivary gland morphologyHPOHP:0010286
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
2 names
Resolves to: Kimura disease
- Also called
- eosinophilic lymphogranulomaKimura's disease