kidney Wilms tumor
Findings
No curated finding names kidney Wilms tumor yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An embryonal pediatric tumor of the kidney which may also be seen rarely in adults. The peak incidence of Wilms tumor is between the second and fifth year of life. Microscopically, it is composed of a mixture of cellular elements (blastemal, stromal, and epithelial). The most common sites of metastasis include the regional lymph nodes, lungs, and liver.
Definition from the Mondo Disease Ontology (MONDO:0019004), read 2026-09-29. CC BY 4.0.
Features
27 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abdominal massHPOHP:0031500
- Very frequent (80% to 99% of cases)
- NeoplasmHPOHP:0002664
- Very frequent (80% to 99% of cases)
- NephroblastomaHPOHP:0002667
- Very frequent (80% to 99% of cases)
- Abdominal painHPOHP:0002027
- Frequent (30% to 79% of cases)
- Duplication of renal pelvisHPOHP:0005580
- Frequent (30% to 79% of cases)
- Macroscopic hematuriaHPOHP:0012587
- Frequent (30% to 79% of cases)
- Abnormal uterus morphologyHPOHP:0031105
- Occasional (5% to 29% of cases)
- AnemiaHPOHP:0001903
- Occasional (5% to 29% of cases)
- AniridiaHPOHP:0000526
- Occasional (5% to 29% of cases)
- CryptorchidismHPOHP:0000028
- Occasional (5% to 29% of cases)
- Ectopic kidneyHPOHP:0000086
- Occasional (5% to 29% of cases)
- FeverHPOHP:0001945
- Occasional (5% to 29% of cases)
Show the remaining 15
- HemihypertrophyHPOHP:0001528
- Occasional (5% to 29% of cases)
- Horseshoe kidneyHPOHP:0000085
- Occasional (5% to 29% of cases)
- HypercalcemiaHPOHP:0003072
- Occasional (5% to 29% of cases)
- HypertensionHPOHP:0000822
- Occasional (5% to 29% of cases)
- HypospadiasHPOHP:0000047
- Occasional (5% to 29% of cases)
- LymphadenopathyHPOHP:0002716
- Occasional (5% to 29% of cases)
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
- A kind of
Other names
12 names
Resolves to: kidney Wilms tumor
- Also called
- nephroblastomanephroblastoma, malignantrenal embryonic tumorrenal embryonic tumourrenal Wilms tumorrenal Wilms tumourrenal Wilms' tumorWilms tumor of the kidneyWilms tumour of the kidneyWilms' TumorWilms' tumor of the kidneyWilms' tumour of the kidney