keratosis palmaris et plantaris-clinodactyly syndrome
Findings
No curated finding names keratosis palmaris et plantaris-clinodactyly syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Keratosis palmaris et plantaris-clinodactyly syndrome is characterized by the association of palmoplantar keratosis with clinodactyly of the fifth finger. Less than 20 cases have been described in the literature so far, and the majority of reported patients were of Mexican origin. Transmission is autosomal dominant.
Definition from the Mondo Disease Ontology (MONDO:0007857), read 2026-09-29. CC BY 4.0.
Features
3 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Clinodactyly of the 5th fingerHPOHP:0004209
- Very frequent (80% to 99% of cases)
- Diffuse palmoplantar hyperkeratosisHPOHP:0007447
- Very frequent (80% to 99% of cases)
- HyperhidrosisHPOHP:0000975
- Frequent (30% to 79% of cases)
Where it sits
- A kind of
Other names
1 name
Resolves to: keratosis palmaris et plantaris-clinodactyly syndrome
- Also called
- palmoplantar keratoderma-clinodactyly syndrome