joint laxity, familial
Findings
No curated finding names joint laxity, familial yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A type of Ehlers-Danlos syndrome characterized by generalized joint hypermobility often complicated by dislocation of major joints, particularly the shoulder but in some cases the kneecap. Congenital hip dislocation has also been frequently reported. The syndrome has been described in several families. It is transmitted as an autosomal dominant trait, with high penetrance.
Definition from the Mondo Disease Ontology (MONDO:0007842), read 2026-09-29. CC BY 4.0.
Features
8 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Congenital hip dislocationHPOHP:0001374
- Very frequent (80% to 99% of cases)
- Joint hypermobilityHPOHP:0001382
- Very frequent (80% to 99% of cases)
- Patellar dislocationHPOHP:0002999
- Very frequent (80% to 99% of cases)
- Abnormality of the kneeHPOHP:0002815
- Frequent (30% to 79% of cases)
- Abnormal femur morphologyHPOHP:0002823
- Occasional (5% to 29% of cases)
- Abnormality of the elbowHPOHP:0009811
- Occasional (5% to 29% of cases)
- Inguinal hernia
Where it sits
- A kind of
Other names
5 names
Resolves to: joint laxity, familial
- Also called
- EDS XIEhlers-Danlos syndrome type 11, formerlyfamilial joint instability syndromefamilial joint laxityJoint instability syndrome