isotretinoin-like syndrome
MONDO:0009473Mondo
Findings
No curated finding names isotretinoin-like syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Isotretinoin-like syndrome is a phenocopy of the isotretinoin embryopathy.
Definition from the Mondo Disease Ontology (MONDO:0009473), read 2026-09-29. CC BY 4.0.
Features
28 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- MicrotiaHPOHP:0008551
- Very frequent (80% to 99% of cases)
- Abnormal aortic arch morphologyHPOHP:0012303
- Frequent (30% to 79% of cases)
- Abnormal cardiac atrium morphologyHPOHP:0005120
- Frequent (30% to 79% of cases)
- Abnormal cardiac ventricle morphologyHPOHP:0001713
- Frequent (30% to 79% of cases)
- Abnormal posterior cranial fossa morphologyHPOHP:0000932
- Frequent (30% to 79% of cases)
- Abnormality of the pulmonary veinsHPOHP:0011718
- Frequent (30% to 79% of cases)
- Anteverted naresHPOHP:0000463
- Frequent (30% to 79% of cases)
- Aortic valve stenosisHPOHP:0001650
- Frequent (30% to 79% of cases)
- Aplasia/Hypoplasia of the inner earHPOHP:0008774
- Frequent (30% to 79% of cases)
- Atresia of the external auditory canalHPOHP:0000413
- Frequent (30% to 79% of cases)
- Bicuspid aortic valveHPOHP:0001647
- Frequent (30% to 79% of cases)
- Bilateral sensorineural hearing impairmentHPOHP:0008619
- Frequent (30% to 79% of cases)
Reported absent (2)
- Decreased total lymphocyte countHPOHP:0001888
- HypocalcemiaHPOHP:0002901
Show the remaining 16
- Cleft palateHPOHP:0000175
- Frequent (30% to 79% of cases)
- Conotruncal defectHPOHP:0001710
- Frequent (30% to 79% of cases)
- Feeding difficultiesHPOHP:0011968
- Frequent (30% to 79% of cases)
- Gastroesophageal refluxHPOHP:0002020
- Frequent (30% to 79% of cases)
- HydrocephalusHPOHP:0000238
- Frequent (30% to 79% of cases)
- Inguinal herniaHPOHP:0000023
- Frequent (30% to 79% of cases)
Where it sits
Other names
2 names
Resolves to: isotretinoin-like syndrome
- Also called
- Kawashima syndromemicrotia-aortic arch syndrome