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Reference

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A reference for what the literature reports. Not medical advice.

Disease

isolated thyrotropin-releasing hormone deficiency

MONDO:0010140Mondo

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Findings

No curated finding names isolated thyrotropin-releasing hormone deficiency yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

Hypothyroidism due to dysfunction of the hypothalamus, assumed to result in reduced secretion of thyrotropin- releasing hormone.

Definition from the Mondo Disease Ontology (MONDO:0010140), read 2026-09-29. CC BY 4.0.

Where it sits

A kind of: central congenital hypothyroidism

Other names

8 names

Resolves to: isolated thyrotropin-releasing hormone deficiency

Also called: isolated prothyroliberin deficiencyisolated protirelin deficiencyisolated thyroliberin deficiencyisolated thyrotropin-releasing factor deficiencyisolated TRF deficiencyisolated TRH deficiencyisolated TSH-releasing factor deficiencytertiary hypothyroidism