isolated hemihyperplasia
MONDO:0009331Mondo
Findings
No curated finding names isolated hemihyperplasia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Isolated hemihyperplasia is a rare overgrowth syndrome characterized by an asymmetric regional body overgrowth, involving at least one limb, and associated with an increased risk of developing embryonal tumors, principally nephroblastoma and hepoblastoma.
Definition from the Mondo Disease Ontology (MONDO:0009331), read 2026-09-29. CC BY 4.0.
Features
12 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Asymmetry of the thoraxHPOHP:0001555
- Very frequent (80% to 99% of cases)
- HemihypertrophyHPOHP:0001528
- Very frequent (80% to 99% of cases)
- ScoliosisHPOHP:0002650
- Very frequent (80% to 99% of cases)
- Abnormality of the dentitionHPOHP:0000164
- Frequent (30% to 79% of cases)
- Facial asymmetryHPOHP:0000324
- Frequent (30% to 79% of cases)
- Mild intellectual disabilityHPOHP:0001256
- Frequent (30% to 79% of cases)
- Abnormal cardiovascular system morphologyHPOHP:0030680
- Occasional (5% to 29% of cases)
- CryptorchidismHPOHP:0000028
- Occasional (5% to 29% of cases)
- Impaired pain sensationHPOHP:0007328
- Occasional (5% to 29% of cases)
- Inguinal herniaHPOHP:0000023
- Occasional (5% to 29% of cases)
- MyelomeningoceleHPOHP:0002475
- Occasional (5% to 29% of cases)
- NephroblastomaHPOHP:0002667
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
4 names
Resolves to: isolated hemihyperplasia
- Also called
- hemi 3 syndromeHemicorporal hypertrophyhemihypertrophyisolated hemihypertrophy