isolated congenital hypoglossia/aglossia
MONDO:0013003Mondo
Findings
No curated finding names isolated congenital hypoglossia/aglossia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Isolated aglossia and hypoglossia are terms covering the spectrum from partial to total absence of the tongue. These congenital malformations have been classified as part of the group of oromandibular-limb hypogenesis syndromes (OLHS).
Definition from the Mondo Disease Ontology (MONDO:0013003), read 2026-09-29. CC BY 4.0.
Features
16 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Delayed speech and language developmentHPOHP:0000750
- Very frequent (80% to 99% of cases)
- DyspneaHPOHP:0002094
- Very frequent (80% to 99% of cases)
- Feeding difficultiesHPOHP:0011968
- Very frequent (80% to 99% of cases)
- Nasogastric tube feeding in infancyHPOHP:0011470
- Very frequent (80% to 99% of cases)
- Aplasia/Hypoplasia of fingersHPOHP:0006265
- Frequent (30% to 79% of cases)
- Gastrostomy tube feeding in infancyHPOHP:0011471
- Frequent (30% to 79% of cases)
- MicroglossiaHPOHP:0000171
- Frequent (30% to 79% of cases)
- MicrognathiaHPOHP:0000347
- Frequent (30% to 79% of cases)
- Respiratory distressHPOHP:0002098
- Frequent (30% to 79% of cases)
- Upper airway obstructionHPOHP:0002781
- Frequent (30% to 79% of cases)
- Weight lossHPOHP:0001824
- Frequent (30% to 79% of cases)
- Abnormal epiglottis morphologyHPOHP:0005483
- Occasional (5% to 29% of cases)
Show the remaining 4
- Aspiration pneumoniaHPOHP:0011951
- Occasional (5% to 29% of cases)
- Cleft palateHPOHP:0000175
- Occasional (5% to 29% of cases)
- HamartomaHPOHP:0010566
- Occasional (5% to 29% of cases)
- Temporomandibular joint ankylosisHPOHP:0012478
- Occasional (5% to 29% of cases)
Where it sits
- Narrower terms (2)