iron overload, susceptibility to
MONDO:0859316Mondo
Findings
No curated finding names iron overload, susceptibility to yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Late onset · Middle age onset
HPO, annotations 2026-09-02
Features
6 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Increased circulating ferritin concentrationHPOHP:0003281
- 8 of 8 reported patients
- Elevated circulating hepcidin concentrationHPOHP:0031877
- 4 of 6 reported patients
- Elevated transferrin saturationHPOHP:0012463
- 4 of 8 reported patients
- ArthralgiaHPOHP:0002829
- 2 of 8 reported patients
- Type II diabetes mellitusHPOHP:0005978
- 1 of 8 reported patients
- Elevated hepatic iron concentrationHPOHP:0012465
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- BMP6HGNC:1073
- Moderate · PanelApp Australia · Autosomal dominant · 2025
- Limited · ClinGen · Autosomal dominant · 2025
Where it sits
- A kind of