intellectual disability, X-linked, syndromic, 35
MONDO:0030908Mondo
Findings
No curated finding names intellectual disability, X-linked, syndromic, 35 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- X-linked recessive inheritance
- Onset and course
- Congenital onset · Fetal onset
HPO, annotations 2026-09-02
Features
64 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Cerebellar hypoplasiaHPOHP:0001321
- 2 of 2 reported patients
- CryptorchidismHPOHP:0000028
- 3 of 3 reported patients · Male
- 1 of 2 reported patients
- Gait ataxiaHPOHP:0002066
- 2 of 2 reported patients
- Global developmental delayHPOHP:0001263
- 4 of 4 reported patients
- HypotoniaHPOHP:0001252
- 3 of 3 reported patients
- Intellectual disabilityHPOHP:0001249
- 4 of 4 reported patients
- Long philtrumHPOHP:0000343
- 2 of 2 reported patients
- Mandibular prognathiaHPOHP:0000303
- 3 of 3 reported patients
- Recurrent infectionsHPOHP:0002719
- 3 of 3 reported patients
- Spondyloepiphyseal dysplasiaHPOHP:0002655
- 2 of 2 reported patients
- Delayed speech and language developmentHPOHP:0000750
- 5 of 6 reported patients
- Growth delayHPOHP:0001510
- 4 of 5 reported patients
Show the remaining 52
- SeizureHPOHP:0001250
- 4 of 5 reported patients
- DolichocephalyHPOHP:0000268
- 3 of 4 reported patients
- PolyhydramniosHPOHP:0001561
- 3 of 4 reported patients · Fetal onset
- Smooth philtrumHPOHP:0000319
- 3 of 4 reported patients
- MicrocephalyHPOHP:0000252
- 5 of 7 reported patients
- 2-3 toe cutaneous syndactylyHPOHP:0005709
- 2 of 3 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- RPL10HGNC:10298
- Definitive · G2P · X-linked · 2020
- Strong · Labcorp Genetics (formerly Invitae) · X-linked · 2022
- Strong · PanelApp Australia · X-linked · 2025
- Moderate · Ambry Genetics · X-linked · 2018
Where it sits
Other names
1 name
Resolves to: intellectual disability, X-linked, syndromic, 35
- Also called
- intellectual developmental disorder, X-linked, syndromic, 35, X-linked recessive