intellectual developmental disorder, X-linked 111
MONDO:0957203Mondo
Findings
No curated finding names intellectual developmental disorder, X-linked 111 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- X-linked inheritance
- Onset and course
- Infantile onset
HPO, annotations 2026-09-02
Features
22 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Global developmental delayHPOHP:0001263
- 8 of 8 reported patients
- Intellectual disabilityHPOHP:0001249
- 8 of 8 reported patients
- AnxietyHPOHP:0000739
- 7 of 8 reported patients
- Unsteady gaitHPOHP:0002317
- 4 of 6 reported patients
- Delayed speech and language developmentHPOHP:0000750
- 5 of 8 reported patients
- Autistic behaviorHPOHP:0000729
- 4 of 8 reported patients
- Feeding difficultiesHPOHP:0011968
- 4 of 8 reported patients
- KyphoscoliosisHPOHP:0002751
- 4 of 8 reported patients
- Reduced cerebral white matter volumeHPOHP:0034295
- 3 of 6 reported patients
- SeizureHPOHP:0001250
- 3 of 8 reported patients
- Aggressive behaviorHPOHP:0000718
- 2 of 8 reported patients
- HyperactivityHPOHP:0000752
- 2 of 8 reported patients
Show the remaining 10
- SpasticityHPOHP:0001257
- 2 of 8 reported patients
- Corpus callosum atrophyHPOHP:0007371
- 1 of 6 reported patients
- Hippocampal atrophyHPOHP:0410170
- 1 of 6 reported patients
- Thin corpus callosumHPOHP:0033725
- 1 of 6 reported patients
- VentriculomegalyHPOHP:0002119
- 1 of 6 reported patients
- Absent speechHPOHP:0001344
- 1 of 8 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- SLITRK2HGNC:13449
- Strong · PanelApp Australia · X-linked · 2025
- Limited · Ambry Genetics · X-linked · 2024