insulin-resistance syndrome type B
MONDO:0016464Mondo
Findings
No curated finding names insulin-resistance syndrome type B yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Type B insulin-resistance syndrome belongs to the group of extreme insulin-resistance syndromes (which includes leprechaunism, the lipodystrophies, Rabson-Mendenhall syndrome, and type A insulin resistance syndrome) and occurs in the context of immune dysfunction.
Definition from the Mondo Disease Ontology (MONDO:0016464), read 2026-09-29. CC BY 4.0.
Features
50 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal circulating fatty acid concentrationHPOHP:0004359
- Very frequent (80% to 99% of cases)
- Abnormal oral glucose toleranceHPOHP:0004924
- Very frequent (80% to 99% of cases)
- Acanthosis nigricansHPOHP:0000956
- Very frequent (80% to 99% of cases)
- AutoimmunityHPOHP:0002960
- Very frequent (80% to 99% of cases)
- Elevated erythrocyte sedimentation rateHPOHP:0003565
- Very frequent (80% to 99% of cases)
- Fasting hyperinsulinemiaHPOHP:0008283
- Very frequent (80% to 99% of cases)
- Glucose intoleranceHPOHP:0001952
- Very frequent (80% to 99% of cases)
- HyperglycemiaHPOHP:0003074
- Very frequent (80% to 99% of cases)
- HyperinsulinemiaHPOHP:0000842
- Very frequent (80% to 99% of cases)
- HypotriglyceridemiaHPOHP:0012153
- Very frequent (80% to 99% of cases)
- Insulin resistanceHPOHP:0000855
- Very frequent (80% to 99% of cases)
- Postprandial hyperglycemiaHPOHP:0011998
- Very frequent (80% to 99% of cases)
Show the remaining 38
- Systemic lupus erythematosusHPOHP:0002725
- Very frequent (80% to 99% of cases)
- Weight lossHPOHP:0001824
- Very frequent (80% to 99% of cases)
- Abnormal circulating leptin concentrationHPOHP:0004361
- Frequent (30% to 79% of cases)
- Abnormal circulating lipid concentrationHPOHP:0003119
- Frequent (30% to 79% of cases)
- Abnormality of body weightHPOHP:0004323
- Frequent (30% to 79% of cases)
- Antinuclear antibody positivityHPOHP:0003493
Where it sits
- A kind of